​Statistics coming from the District Health Information System (DHIS) show a significant decrease in HIV infections in Gauteng from 2020 to 2024.
For the different age groups from 15- 24 years old, in 2020, the province recorded a 2.9% HIV incidence (HIV new infections) whereas in 2024, 1% was reported.  The same trend has been reported amongst those aged between 25 - 49, as in 2020, a 5.1% HIV incidence (HIV new infections) was recorded while in 2024, 2.9% was reported. 
The new HIV infection statistics suggest that more people are accessing HIV prevention treatment and opting in on Pre-Exposure Prophylaxes (PrEP) as an HIV prevention measure. PrEP uptake in the province has significantly improved since its introduction in 2019, as a game changing HIV prevention intervention, Gauteng has initiated 105 924 individuals on PrEP from February 2024 to December 2024. With the provision a comprehensive package of HIV prevention and treatment services provided at our health care facilities and at community level, the province has a decline in new HIV infections.
In February 2024, the Gauteng province screened a total of 30 676 males for STI's of which 7 468 presented with a symptom and was treated for STI's. This translated to the province recording 18.7% male urethritis incidence. Whereas in December 2024, a total of the 39 877 males were screened for STIs, and 5 713 presented with a symptom and were treated. 
It also translates to the province reporting a 13.1% Male Urethritis Syndrome (MUS) Incidence, indicating a slight decline in the MUS incidence from the total number of Males screened for STI's. With intensified, and focused STI and HIV prevention interventions such as STI screening, health education drives, condom distribution, and HIV testing at various "hotspots", institutions of higher learning we have noted a decrease in the incidence.  
Based on the National trends for Male Urethritis Syndrome Incidence, Gauteng province Districts reported low cases in comparison to other high burden, and densely populated Provinces in South Africa. This indicator informs of sexual behaviour, and it is aimed at reducing high risk sexual behaviour as well as increasing condom use. MUS is often caused by the Neisseria gonorrhoeae bacterium. The next most common cause is Chlamydia trachomatis.
Risky behaviours such as having multiple sexual partners and engaging in unprotected sex, are prevalent in some populations and contribute to the spread of STIs. Despite considerable efforts to identify simple interventions that can reduce risky sexual behaviour, behaviour change remains a complex challenge. 
The GDoH has implemented a combination of prevention intervention approaches which incorporate STI components in these areas such as the promotion of consistent use of male and female condoms which are free and available in health facilities. We are encouraging our community to reduce the number of sexual partners, get tested for HIV, notice the signs and symptoms and seek immediate treatment, and delayed sexual debut. 
MEC Nkomo-Ralehoko urged all those who are sexually active to use male and female condoms which they can access for free at their local healthcare centres to protect themselves against STIs and HIV. 
Using a condom for all types of sex is the best way to avoid STIs and HIV and vaccines (especially for young girls) can prevent certain STIs such as the Human Papillomavirus. Reducing the number of sexual partners you have and not mixing alcohol, drugs and sex also means you're less likely to get infected.
In addition, the GDoH urges that taking PrEP daily is an HIV prevention option. The pill is available at all health care facilities. However, the best way to protect against STIs is to practice safe sex and to avoid risky sexual behavior. Consistent and correct condom use will protect against STI and also prevent unplanned pregnancy and male circumcision done safely at a clinic or hospital can reduce the risk of HIV and STIs in men. It is very important to go to the clinic for treatment if you have any signs and symptoms of STI's.   It is also important to notify your current or recent sexual partners so that they can also be treated at the clinic.